生物物理化學出版了化學和物理領域的原著和評論，直接影響生物現象。從動力學、熱力學、時空組織、核磁共振和x射線結構生物學等方面對生物大分子、生物活性分子、大分子組件和細胞組分的性質進行定量分析，以及單分子檢測，是本雜志的一個主要焦點。生物大分子系統的理論和計算處理、大分子相互作用、調節控制和系統生物學也受到雜志的關注。該雜志定期發表文章、信件和受邀評論。不屬于期刊范圍和興趣范圍的手稿將被退回給作者，而不進行深入的審查。相關的手稿會在收到后3周內迅速審查，并作出決定。信件是短文（最多6頁印刷），報告結果具有異常的及時性和重要性。信件的決定是在收到后1-2周內作出的，出版只提供給需要輕微修訂的手稿。評論是由編輯邀請發表的，但隨時歡迎提出建議。作者現在可以在ScienceDirect網站http://www.sciencedirect.com/science/journal/03014622上提交在線出版物的補充材料。有關更多信息，請參閱作者指南http://www.elsevier.com/journals/biophysical-chemistry/0301-4622/guide-for-authors。

Biophysical Chemistry publishes original work and reviews in the areas of chemistry and physics directly impacting biological phenomena. Quantitative analysis of the properties of biological macromolecules, biologically active molecules, macromolecular assemblies and cell components in terms of kinetics, thermodynamics, spatio-temporal organization, NMR and X-ray structural biology, as well as single-molecule detection represent a major focus of the journal. Theoretical and computational treatments of biomacromolecular systems, macromolecular interactions, regulatory control and systems biology are also of interest to the journal.The journal publishes regular articles, letters and invited reviews. Manuscripts that fall outside the scopes and interests of the journal are returned to the Authors without in-depth review. Relevant manuscripts are reviewed expeditiously with decisions generally made within 3 weeks from receipt. Letters are short articles (6 printed pages maximum) reporting results of unusual timeliness and significance. Decisions on Letters are made within 1-2 weeks from receipt and publication is offered only to manuscripts requiring minor revision. Reviews are published by invitation from the Editors, but suggestions are welcome at any time. Authors can now submit supplementary material for online publication on ScienceDirect http://www.sciencedirect.com/science/journal/03014622. See our Guide for Authors http://www.elsevier.com/journals/biophysical-chemistry/0301-4622/guide-for-authors for more information.