《結構》旨在發表在結構生物學領域具有特殊興趣的論文。該雜志致力于成為結構生物學家，以及生物學家和生物化學家對大分子結構和功能感興趣的基本讀物。《結構》強烈鼓勵提交關于生物功能和機制的結構和分子見解的手稿。其他涉及結構生物學基本問題的報告，例如蛋白質進化、折疊和/或設計的基于結構的檢查，也將被優先考慮。我們將考慮任何方法的應用，實驗或計算，在高或低分辨率，進行結構研究，只要該方法是適當的生物，功能和機械問題的解決。同樣，描述單分子生物學機制分析的報告也很受歡迎。一般來說，編輯們鼓勵提交結構研究，這些研究由處理結構-活動關系的額外實驗系統進行驗證，并且不會考慮只報告結構信息的研究，除非所調查的結構具有特殊和廣泛的興趣。

Structure aims to publish papers of exceptional interest in the field of structural biology. The journal strives to be essential reading for structural biologists, as well as biologists and biochemists that are interested in macromolecular structure and function. Structure strongly encourages the submission of manuscripts that present structural and molecular insights into biological function and mechanism. Other reports that address fundamental questions in structural biology, such as structure-based examinations of protein evolution, folding and/or design, will also be considered favorably. We will consider the application of any method, experimental or computational, at high or low resolution, to conduct structural investigations, as long as the method is appropriate for the biological, functional, and mechanistic question(s) being addressed. Likewise, reports describing single molecule analysis of biological mechanisms are welcome. In general, the editors encourage submission of structural studies that are validated by additional experimental systems that address structure-activity relationships, and will not consider studies that solely report structural information unless the structure under investigation is of exceptional and broad interest.